Cartilage Lacuna‐Inspired Microcarriers Drive Hyaline Neocartilage Regeneration (Adv. Mater. 30/2023)
نویسندگان
چکیده
Cartilage Tissue Engineering In article number 2212114, Wenguo Cui, Qi Gu, Ming-Zhu Zhang, and co-workers introduce novel cartilage lacuna-inspired microcarriers with geometric constraints to repress chondrocyte dedifferentiation by inhibiting Wnt signaling. The biomimetic display favorable cytocompatibility drive robust hyaline chondrocyte-derived neocartilage formation. This study paves the way for deciphering geometrical insights into interactional mechanism of mechanotransduction in regulating cell fate.
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ژورنال
عنوان ژورنال: Advanced Materials
سال: 2023
ISSN: ['1521-4095', '0935-9648']
DOI: https://doi.org/10.1002/adma.202370216